Malignant mitral prolapse: predictive signs

Authors

  • Andrés Provencio Regidor Cardiology Service. Cardiovascular Institute. Hospital Clínico San Carlos, Madrid, Spain
  • Eva Gutiérrez Ortiz Cardiology Service. Heart Institute. San Carlos Clinical Hospital, Madrid, Spain.
  • José Juan Gómez de Diego Cardiology Service. Cardiovascular Institute. Hospital Clínico San Carlos, Madrid, Spain

DOI:

https://doi.org/10.37615/retic.v5n3a3

Keywords:

malignant mitral prolapse, Barlow síndrome, myxomatous mitral valve

Abstract

Mitral valve prolapse (MVP) is a highly prevalent valve disease, usually considered benign. However, in a subgroup of patients it is associated with an unfavorable clinical course, ranging from severe valvular insufficiency to sudden death from arrhythmic cause. In this article, methods for a complete valve evaluation with echocardiography and cardiac magnetic resonance are reviewed, including some parameters that have recently been identified as predictors of the development of cardiomyopathy and a worse prognosis.

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References

Nishimura RA, McGoon MD, Shub C, Miller FA, Ilstrup DM, Tajik AJ. Echocardiographically Documented Mitral-Valve Prolapse. N Engl J Med. 21 de noviembre de 1985;313(21):1305-9. DOI: https://doi.org/10.1056/NEJM198511213132101

Basso C, Iliceto S, Thiene G, Perazzolo Marra M. Mitral Valve Prolapse, Ventricular Arrhythmias, and Sudden Death. Circulation. 10 de septiembre de 2019;140(11):952-64. DOI: https://doi.org/10.1161/CIRCULATIONAHA.118.034075

Sriram CS, Syed FF, Ferguson ME, Johnson JN, Enriquez-Sarano M, Cetta F, et al. Malignant bileaflet mitral valve prolapse syndrome in patients with otherwise idiopathic out-of-hospital cardiac arrest. J Am Coll Cardiol. 16 de julio de 2013;62(3):222-30. DOI: https://doi.org/10.1016/j.jacc.2013.02.060

Slavich M, Palmisano A, Pannone L, Agricola E, Margonato A, Esposito A. Hidden Danger Behind the Prolapse. Circ Cardiovasc Imaging. octubre de 2019;12(10):e009639. DOI: https://doi.org/10.1161/CIRCIMAGING.119.009639

Marra MP, Basso C. Mechanical dispersion and arrhythmic mitral valve prolapse: substrate and trigger in electrical instability. Heart. 1 de julio de 2019;105(14):1053-4. DOI: https://doi.org/10.1136/heartjnl-2019-314788

Muthukumar L, Rahman F, Jan MF, Shaikh A, Kalvin L, Dhala A, et al. The Pickelhaube Sign. JACC Cardiovasc Imaging. septiembre de 2017;10(9):1078-80. DOI: https://doi.org/10.1016/j.jcmg.2016.09.016

Ermakov S, Gulhar R, Lim L, Bibby D, Tseng Z, Abraham T, et al. Delayed time to peak strain identifies mitral valve prolapse patients at higher arrhythmic risk. J Am Coll Cardiol. 10 de marzo de 2018;71(11, Supplement):A1551. DOI: https://doi.org/10.1016/S0735-1097(18)32092-8

van Wijngaarden SE, Abou R, Hiemstra YL, Ajmone Marsan N, Bax JJ, Delgado V. Regional Left Ventricular Myocardial Mechanics in Degenerative Myxomatous Mitral Valve Disease: A Comparison Between Fibroelastic Deficiency and Barlow’s Disease. JACC Cardiovasc Imaging. septiembre de 2018;11(9):1362-4. DOI: https://doi.org/10.1016/j.jcmg.2017.11.012

Brainin P, Biering‐Sørensen SR, Møgelvang R, Søgaard P, Jensen JS, Biering‐Sørensen T. Postsystolic Shortening by Speckle Tracking Echocardiography Is an Independent Predictor of Cardiovascular Events and Mortality in the General Population. J Am Heart Assoc. 20 de marzo de 2018;7(6):e008367. DOI: https://doi.org/10.1161/JAHA.117.008367

Constant Dit Beaufils AL, Huttin O, Jobbe-Duval A, Senage T, Filippetti L, Piriou N, et al. Replacement Myocardial Fibrosis in Patients With Mitral Valve Prolapse: Relation to Mitral Regurgitation, Ventricular Remodeling, and Arrhythmia. Circulation. 4 de mayo de 2021;143(18):1763-74. DOI: https://doi.org/10.1161/CIRCULATIONAHA.120.050214

Russo R, Maan A, Apostolidou E, Khorasani-Zadeh A, Byrnes S, Chebaya P, et al. Identification of a High-risk Subgroup With Malignant Mitral Valve Prolapse Who Are Predisposed to Sudden Cardiac Death: A Review. Crit Pathw Cardiol. marzo de 2021;20(1):31-5. DOI: https://doi.org/10.1097/HPC.0000000000000242

Kitkungvan D, Nabi F, Kim RJ, Bonow RO, Khan MA, Xu J, et al. Myocardial Fibrosis in Patients With Primary Mitral Regurgitation With and Without Prolapse. J Am Coll Cardiol. agosto de 2018;72(8):823-34. DOI: https://doi.org/10.1016/j.jacc.2018.06.048

Published

2022-12-31

How to Cite

1.
Provencio Regidor A, Gutiérrez Ortiz E, Gómez de Diego JJ. Malignant mitral prolapse: predictive signs. Rev Ecocar Pract (RETIC) [Internet]. 2022 Dec. 31 [cited 2024 May 19];5(3):11-5. Available from: https://imagenretic.org/RevEcocarPract/article/view/550

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