Constitutional syndrome for carcinoid tumor: characteristic cardiac involvement
DOI:
https://doi.org/10.37615/retic.v3n1a12Keywords:
carcinoid syndrome, neuroendocrine tumor, acquired valvulopathy.Abstract
Carcinoid tumors are neuroendocrine tumors arising from enterochromaffin cells. The most common localization is the gastrointestinal tract and the bronchia. Carcinoid syndrome is characterized by flushing of the face and trunk, diarrhea, bronchial spasm, and dyspnea. Carcinoid syndrome is a rare cause of acquired valvulopathy, however, between 20-60% of patients have heart involvement being the most common cause of death. We present a case of tricuspid and pulmonary valvular disease secondary to this syndrome with review of the literature.
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Hassan SA, Banchs J, Iliescu C, et al. Carcinoid Heart Disease: a Comprehensive Review. Heart 2017; 103 (19): 1488-1495. doi: https://doi.org/10.1007/s11886-019-1207-8
Miyasaka R, Mehta A, Pettersson GB, et al. Carcinoid Tricuspid Valve Disease: Applications of Three Dimensional Transesophageal Echocardiography. Circ Cardiovasc Imaging 2019; 12: e009555. doi: https://doi.org/10.1161/CIRCIMAGING.119.009555
Davar J, Connolly HM, Caplin ME, et al. Diagnosing and Managing Carcinoid Heart Disease in Patients With Neuroendocrine Tumors: An Expert Statement. J Am Coll Cardiol 2017; 69: 1288-1304. doi: https://doi.org/10.1016/j.jacc.2016.12.030
Dashwood A, Rahman A, Pavicic M. Carcinoid heart disease. Eur Heart J 2015; 36 :2326. doi: https://doi.org/10.1093/eurheartj/ehv070
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Copyright (c) 2020 Leyre Sáenz de Pipaon Ayala, José Ramírez Batista, Laura Hurtado Carrillo, Irene Ariño Pérez de Zabalza, Pedro María Azcárate Agüero
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