Platypnea-orthodeoxia syndrome due to patent foramen ovale diagnosed by echocardiography
DOI:
https://doi.org/10.37615/retic.v9n2a8Keywords:
platypnea-orthodeoxia syndrome, patent foramen ovale, contrast echocardiography, right-to-left shuntAbstract
We present the case of a 71-year-old woman admitted for episodes of dyspnoea and desaturation with postural variation, characterised by desaturation when standing and improvement when lying down, suggestive of platypnoea-orthodeoxia syndrome. Transthoracic and transoesophageal echocardiography revealed a large patent foramen ovale with a significant shunt. Closure of the defect using an Amplatzer™-type device completely resolved the symptoms.
Downloads
References
Agrawal A, Palkar A, Talwar A. The multiple dimensions of platypnea-orthodeoxia syndrome: A review. Respir Med. 2017;129:31-38. doi: https://doi.org/10.1016/j.rmed.2017.05.016
Cheng TO. Platypnea-orthodeoxia syndrome: etiology, differential diagnosis, and management. Catheter Cardiovasc Interv. 1999;47(1):64-66. doi: https://doi.org/10.1002/(SICI)1522-726X(199905)47:1<64::AID-CCD15>3.0.CO;2-6
Mojadidi MK, Gevorgyan R, Noureddin N, Tobis JM. The effect of patent foramen ovale closure in patients with platypnea-orthodeoxia syndrome. Catheter Cardiovasc Interv. 2015;86(4):701-707. doi: https://doi.org/10.1002/ccd.25998
Bertaux G, Eicher JC, Petit A, Dobšák P, Wolf JE. Anatomic interaction between the aortic root and the atrial septum: a prospective echocardiographic study. J Am Soc Echocardiogr. 2007;20(4):409-414. doi: https://doi.org/10.1016/j.echo.2006.09.007
Sanikommu V, Lasorda D, Poornima I. Anatomical factors triggering platypnea-orthodeoxia in adults. Clin Cardiol. 2009;32(11):E55-E57. doi: https://doi.org/10.1002/clc.20520
Rodrigues P, Palma P, Sousa-Pereira L. Platypnea-orthodeoxia syndrome in review: defining a new disease? Cardiology. 2012;123(1):15-23. doi: https://doi.org/10.1159/000338798
Guerin P, Lambert V, Godart F, et al. Transcatheter closure of patent foramen ovale in patients with platypnea-orthodeoxia: results of a multicentric French registry. Cardiovasc Intervent Radiol. 2005;28(2):164-168. doi: https://doi.org/10.1007/s00270-004-0151-8
Blanche C, Noble S, Roffi M, et al. Platypnea-orthodeoxia syndrome in the elderly treated by percutaneous patent foramen ovale closure: a case series and literature review. Eur J Intern Med. 2013;24(8):813-817. doi: https://doi.org/10.1016/j.ejim.2013.05.013
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Alberto Funes Almendros, Yassin Daoud, Asier Rubio Martínez, Óscar García Durán, Miriam García Cocera

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
RETIC is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license https://creativecommons.org/licenses/by-nc-nd/4.0 which allows sharing, copying and redistribution of the material in any medium or format, under the following terms:
- Attribution: you must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests that the licensor endorses you or your use.
- Non-commercial: you may not use the material for commercial purposes.
- No Derivatives: if you remix, transform or build upon the material, you may not distribute the modified material.
- No Additional Restrictions: you may not apply legal terms or technological measures that legally restrict others from doing anything permitted by the license.