Update on bicuspid aortic valve and associated complications
DOI:
https://doi.org/10.37615/retic.n3a3Keywords:
bicuspide aortic valve, aortic dilatation, valve surgery.Abstract
Bicuspid aortic valve (BAV) is the most common congenital heart disease affecting 1-2% of the population. It affects more frequently males than females with a ratio of 3:1. Despite the fact that it has been historically considered a relatively benign disease, 35% of individuals with BAV will develop complications throughout life such as valve dysfunction, aortic aneurysm or aortic dissection. In spite of the relevance of this disease many aspects are not still clarified.
The aim of this article is to show an updated version of the basic aspects of this pathology with emphasis on the latest developments related to the diagnosis, evolution and associated complications from a cardiac imaging viewpoint.
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Tanaka R, Yoshioka K, Niinuma H, et al. Diagnostic value of cardiac CT in the evaluation of bicuspid aortic stenosis: Comparison with echocardiography and operative findings. AJR Am J Roentgenol 2010; 195 (4): 895-899. DOI: https://doi.org/10.2214/AJR.09.3164
Erbel R, Aboyans V, Boileau C, et al. 2014 ESC guidelines on the diagnosis and treatment of aortic diseases. Eur Heart J 2014; 35 (41): 2.873-2.926. DOI: https://doi.org/10.1093/eurheartj/ehu281
Beppu S, Suzuki S, Matsuda H, et al. Rapidity of progression of aortic stenosis in patients with congenital bicuspid aortic valves. Am J Cardiol 1993; 71 (4): 322-327. DOI: https://doi.org/10.1016/0002-9149(93)90799-I
Wallby L, Janerot-Sjöberg B, Steffensen T, Broqvist M. T lymphocyte infiltration in non-rheumatic aortic stenosis: A comparative descriptive study between tricuspid and bicuspid aortic valves. Heart 2002; 88 (4): 348-351. DOI: https://doi.org/10.1136/heart.88.4.348
Michelena HI, Desjardins VA, Avierinos JF, et al. Natural history of asymptomatic patients with normally functioning or minimally dysfunctional bicuspid aortic valve in the community. Circulation 2008; 117 (21): 2.776-2.784. DOI: https://doi.org/10.1161/CIRCULATIONAHA.107.740878
Tzemos N, Therrien J, Thanassoulis G, et al. Outcomes in adults with bicuspid aortic valves. JAMA 2008; 300 (11): 1.317-1.325. DOI: https://doi.org/10.1001/jama.300.11.1317
Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: A report of the American college of cardiology/American heart association task force on practice guidelines. J Am Coll Cardiol 2014; 63 (22): 2.438-2.488.
Vahanian A, Alfieri O, Andreotti F, et al. Guidelines on the management of valvular heart disease (version 2012). Eur Heart J 2012; 33 (19): 2.451-2.496.
Keane MG, Wiegers SE, Plappert T, et al. Bicuspid aortic valves are associated with aortic dilatation out of proportion to coexistent valvular lesions. Circulation 2000; 102 (19 Suppl 3): III35-39. DOI: https://doi.org/10.1161/01.CIR.102.suppl_3.III-35
Schaefer BM, Lewin MB, Stout KK, et al. The bicuspid aortic valve: An integrated phenotypic classification of leaflet morphology and aortic root shape. Heart 2008; 94 (12): 1.634-1.638. DOI: https://doi.org/10.1136/hrt.2007.132092
Corte A Della, Bancone C, Buonocore M, et al. Pattern of ascending aortic dimensions predicts the growth rate of the aorta in patients with bicuspid aortic valve. JACC Cardiovasc Imaging 2013; 6 (12): 1.301-1.310. DOI: https://doi.org/10.1016/j.jcmg.2013.07.009
Detaint D, Michelena HI, Nkomo VT, et al. Aortic dilatation patterns and rates in adults with bicuspid aortic valves: A comparative study with Marfan syndrome and degenerative aortopathy. Heart 2014; 100 (2): 126-134. DOI: https://doi.org/10.1136/heartjnl-2013-304920
Mahadevia R, Barker AJ, Schnell S, et al. Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy. Circulation 2014; 129 (6): 673-682. DOI: https://doi.org/10.1161/CIRCULATIONAHA.113.003026
Biner S, Rafique AM, Ray I, et al. Aortopathy is prevalent in relatives of bicuspid aortic valve patients. J Am Coll Cardiol 2009; 53 (24): 2.288-2.295. DOI: https://doi.org/10.1016/j.jacc.2009.03.027
Huntington K, Hunter AGW, Chan KL. A prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve. J Am Coll Cardiol 1997; 30 (7): 1.809-1.812. DOI: https://doi.org/10.1016/S0735-1097(97)00372-0
Cripe L, Andelfinger G, Martin LJ, et al. Bicuspid aortic valve is heritable. J Am Coll Cardiol 2004; 44 (1): 138-143. DOI: https://doi.org/10.1016/j.jacc.2004.03.050
Guntheroth WG. A Critical Review of the American College of Cardiology/ American Heart Association Practice Guidelines on Bicuspid Aortic Valve With Dilated Ascending Aorta. Am J Cardiol 2008; 102: 107-110. DOI: https://doi.org/10.1016/j.amjcard.2008.02.106
Michelena HI, Khanna AD, Mahoney D, et al. Incidence of aortic complications in patients with bicuspid aortic valves. JAMA 2011; 306 (10): 1.104-1.112. DOI: https://doi.org/10.1001/jama.2011.1286
Hayashida K, Bouvier E, Lefèvre T, et al. Transcatheter aortic valve implantation for patients with severe bicuspid aortic valve stenosis. Circ Cardiovasc Interv 2013; 6 (3): 284-291. DOI: https://doi.org/10.1161/CIRCINTERVENTIONS.112.000084
Girdauskas E, Disha K, Raisin HH, et al. Risk of late aortic events after an isolated aortic valve replacement for bicuspid aortic valve stenosis with concomitant ascending aortic dilation. Eur J CardioThoracic Surg 2012; 42 (5): 832-838. DOI: https://doi.org/10.1093/ejcts/ezs137
McKellar SH, Michelena HI, Li Z, et al. Long-term risk of aortic events following aortic valve replacement in patients with bicuspid aortic valves. Am J Cardiol 2010; 106 (11): 1.626-1.633. DOI: https://doi.org/10.1016/j.amjcard.2010.07.043
Borger MA, Preston M, Ivanov J, et al. Should the ascending aorta be replaced more frequently in patients with bicuspid aortic valve disease? J Thorac Cardiovasc Surg 2004; 128 (5): 677-683. DOI: https://doi.org/10.1016/S0022-5223(04)00984-5
Goland S, Czer LSC, De Robertis MA, et al. Risk Factors Associated With Reoperation and Mortality in 252 Patients After Aortic Valve Replacement for Congenitally Bicuspid Aortic Valve Disease. Ann Thorac Surg 2007; 83 (3): 931-937. DOI: https://doi.org/10.1016/j.athoracsur.2006.10.047
Goel SS, Tuzcu EM, Agarwal S, et al. Comparison of ascending aortic size in patients with severe bicuspid aortic valve stenosis treated with versus without a statin drug. Am J Cardiol 2011; 108 (10): 1.458-1.462. DOI: https://doi.org/10.1016/j.amjcard.2011.06.071
Regeer MV, van Rosendael PJ, Kamperidis V, et al. Effect of statins on aortic root growth rate in patients with bicuspid aortic valve anatomy. Int J Cardiovasc Imaging 2015; 31 (8): 1.583-1.590. DOI: https://doi.org/10.1007/s10554-015-0749-0
Antonini-Canterin F, Hirsu M, Popescu BA, et al. Stage-Related Effect of Statin Treatment on the Progression of Aortic Valve Sclerosis and Stenosis. Am J Cardiol 2008; 102 (6): 738-742. DOI: https://doi.org/10.1016/j.amjcard.2008.04.056
Robledo-Carmona J, Rodríguez-Bailón I, Carrasco-Chinchilla F, et al. Hereditary patterns of bicuspid aortic valve in a hundred families. Int J Cardiol 2013; 168 (4): 3.443-3.449. DOI: https://doi.org/10.1016/j.ijcard.2013.04.180
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Copyright (c) 2016 Laura Galian-Gay, Arturo Evangelista-Masip
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